Los Angeles, CA (May 14, 2025) – A two-vehicle crash involving a red Mazda SUV and a dark-colored Lexus sedan caused injuries Tuesday night on the southbound side of State Route 110 (SR-110), just north of Avenue 43 in Central Los Angeles. The incident occurred at approximately 10:42 p.m. and led to significant delays as emergency services responded.
According to California Highway Patrol reports, the crash left both vehicles in travel lanes, with the Lexus sedan reportedly blocking the slow lane. Witnesses stated the Lexus driver, described as a female (“XRAY”), may have been impaired. The collision also involved two occupants in the Mazda crossover.
Emergency medical teams from the Los Angeles Fire Department were dispatched to the scene and provided treatment for those injured. The number and severity of injuries have not yet been confirmed. A solo-vehicle report was initially logged but was quickly updated to reflect the involvement of multiple vehicles and potential DUI-related factors.
CHP officers are actively investigating the crash, including whether intoxication contributed to the collision. Lane closures were in effect temporarily as responders cleared the vehicles and provided aid.
We extend our hopes for a swift recovery to those injured in this incident.
DUI-Related Crashes on California Freeways
State Route 110, one of the oldest and most traveled highways in Los Angeles, sees high volumes of traffic around the clock. Crashes on this route—especially at night—are often linked to speed, poor lighting, and, unfortunately, impaired driving. Collisions that block active lanes at freeway speeds can have particularly dangerous consequences, leading to multi-car pileups or secondary crashes.
DUI-related crashes are especially concerning due to their preventable nature. Drivers under the influence of alcohol or drugs often display erratic behavior, delayed reaction times, and poor judgment—putting everyone on the road at risk. Even a single moment of impairment can result in life-changing injuries or fatalities.
For victims injured by impaired drivers, recovery may involve a complex mix of emergency treatment, rehabilitation, lost income, and legal proceedings. It is critical to seek professional medical care immediately and to document the incident thoroughly through police reports and medical evaluations.
Legal support is also vital in DUI crash cases, especially when seeking compensation from an at-fault driver who acted negligently or criminally.
If you or someone you love was injured in a crash involving suspected DUI, like the one on SR-110 near Avenue 43, Local Accident Reports is here to support your recovery. Our team can connect you with compassionate legal counsel and trusted medical providers to ensure your rights and well-being are protected. Contact Local Accident Reports today for guidance, resources, and next steps tailored to your needs.