Baltimore, MD (September 21, 2025) – A major crash involving five vehicles left several people injured Friday afternoon at the busy intersection of East Preston Street and North Charles Street. The collision occurred shortly after 2:00 p.m., drawing a large response from Baltimore fire crews, paramedics, and police officers.
Those hurt in the incident were treated at the scene for a variety of injuries before some were transported to nearby hospitals for further care. Traffic in the central district was significantly impacted as first responders worked to stabilize the injured and clear the multiple vehicles involved. Police temporarily closed lanes around the intersection to ensure safety for emergency personnel and passing motorists.
Authorities have not yet provided information on the number of victims hospitalized or the severity of their conditions. Investigators are continuing to examine what led to the multi-vehicle crash in this heavily traveled downtown corridor.
Our thoughts are with the injured individuals as they recover from this serious incident.
Multi-Vehicle Accidents in Maryland
The five-vehicle pileup in Baltimore’s central district demonstrates how quickly city intersections can become dangerous when multiple drivers are involved. Intersections such as East Preston and North Charles Street see heavy volumes of vehicles, pedestrians, and cyclists daily, making them high-risk locations for serious collisions. Friday’s crash not only caused multiple injuries but also disrupted traffic in a densely populated business and residential area.
Multi-vehicle accidents often result from chain-reaction impacts triggered by sudden stops, distracted driving, or failure to yield. In Maryland, urban crashes involving more than two vehicles are increasingly common during peak travel times when congestion is at its worst. The complexity of these incidents also creates challenges for emergency responders, who must treat numerous victims while coordinating roadway safety.
For drivers in Baltimore, heightened awareness at intersections is key. Allowing extra stopping distance, avoiding distractions, and anticipating traffic signals can help prevent dangerous chain-reaction collisions. City officials continue to stress defensive driving habits as an important tool in reducing intersection-related crashes across the state.
Local Accident Reports remind Baltimore residents to take extra precautions when navigating busy cross streets downtown. If you or a loved one were injured in a multi-vehicle accident, you may be entitled to support and resources that can aid in your recovery. Contact Local Accident Reports today to obtain your official crash report and learn about options available to help during this challenging time.
