Beaufort Co, SC (August 18, 2025) – A deadly head-on collision occurred late Sunday evening on U.S. Highway 21, about 4.5 miles north of Beaufort, leaving one person dead and two others injured.
South Carolina Highway Patrol reported that the crash happened around 9:55 p.m. when a 2025 GMC pickup collided head-on with a 2005 Ford pickup. The driver of the GMC tragically died at the scene. The GMC passenger and the Ford driver sustained injuries and were transported to a local hospital for treatment. No further details regarding their conditions have been released at this time.
Troopers confirmed that the crash remains under active investigation.
We extend our deepest condolences to the family of the victim and hope for the recovery of those injured.
Head-On Collisions in South Carolina
Head-on collisions, such as the one reported on US 21, are among the deadliest types of roadway crashes due to the extreme force of impact. These types of incidents often occur on two-lane highways where passing maneuvers, distracted driving, or impaired driving can lead to devastating outcomes.
Victims and their families frequently face significant challenges after such crashes, ranging from the emotional toll of losing a loved one to long-term financial hardships from medical expenses and lost income. In South Carolina, when negligence is found to be a factor, families may pursue wrongful death claims, while injured survivors may seek compensation for damages.
According to state crash data, rural highways like US 21 see a disproportionate share of fatal crashes compared to urban roads, underscoring the need for extra caution in less populated areas. Troopers continue to stress the importance of safe driving practices, including staying alert, reducing speed, and avoiding risky maneuvers.
For those impacted by deadly collisions, understanding available legal and emotional support resources is an important step toward healing and recovery.
If you or someone you know has been injured or lost a loved one in a crash, contact Local Accident Reports for assistance.
