Irvine, CA (January 17, 2026) – An accident on the southbound side of Interstate 405 near Jamboree Rd in Irvine’s business district led to multiple injuries Friday evening, prompting a significant response from local authorities and medical personnel.
First responders, including paramedics and fire crews from Irvine Fire and Rescue, arrived swiftly at the scene shortly after the crash was reported around 7:08 PM PST. Medics worked to assess and treat those injured in the multi-vehicle collision, with at least one person transported to a nearby hospital for additional care. A variety of injuries were reported, though specific medical conditions have not yet been released to the public.
The incident caused major delays on the southbound lanes of I-405 as emergency teams managed the scene and ensured victims received prompt care. Vehicles involved sustained visible damage, but the total number of cars and individuals affected has not yet been confirmed by officials.
Authorities temporarily closed off portions of the freeway to conduct cleanup and begin their investigation. They are currently reviewing evidence and gathering witness accounts to determine what led to the crash. Roadway congestion, visibility conditions, and driver behavior are all expected to be factors under consideration.
Our hearts go out to those hurt in this collision, and we extend our sincerest hopes for a full recovery to everyone affected.
