San Bruno, CA (August 12, 2025) – Emergency crews responded Tuesday night to a multi-vehicle collision on the northbound US 101 connector to westbound I-380. The crash was reported at approximately 9:50 p.m. and involved three vehicles, blocking lanes four and five of the connector ramp. Firefighters, paramedics, and law enforcement officers arrived quickly to provide medical care to those injured.
At least one person sustained injuries in the collision and received on-scene treatment before being transported to a nearby hospital for further evaluation. The incident caused significant traffic delays in the area as crews worked to clear the wreckage and reopen the affected lanes. The California Highway Patrol is continuing its investigation to determine the cause of the crash.
Our thoughts are with everyone injured in this collision, and we wish them a speedy recovery.
Multi-Vehicle Collisions in California
Multi-vehicle crashes, like the one that occurred on the US 101 to I-380 connector in San Bruno, often result in lane closures, extended traffic delays, and a higher risk of injuries due to the chain-reaction nature of the impacts. This interchange is a busy connection point between San Mateo County’s main freeway corridors, with high traffic volumes at nearly all hours of the day. The combination of merging traffic, varying speeds, and driver inattention can quickly lead to serious collisions.
Tuesday night’s crash serves as a reminder for motorists to maintain safe following distances and to remain alert during lane changes or while navigating freeway connectors. Reduced speeds and careful observation of surrounding traffic can help prevent these incidents, particularly in high-congestion areas.
Local Accident Reports encourages drivers to stay patient and attentive, especially when traveling through complex interchanges. If you or someone you love has been injured in a multi-vehicle collision, resources are available to help you navigate your recovery and understand your options. Contact Local Accident Reports today to connect with caring support and guidance designed to meet your needs.