San Francisco, CA (August 13, 2025) – A multi-vehicle collision on southbound Interstate 280 near the San Jose Avenue ramp left three people injured on Saturday afternoon. The crash, which occurred just before 3:05 p.m., prompted a rapid response from multiple emergency units from San Francisco Fire and EMS.
According to dispatch audio, at least two vehicles were confirmed to be involved in the crash, which occurred in the number four lane just north of the Monterey Boulevard exit. First responders requested a second ambulance under Code 3 status to assist with the injured parties. Initial reports indicated that all three patients required medical attention, and emergency teams worked swiftly to assess, treat, and transport the victims.
The exact cause of the crash remains under investigation. Temporary lane closures were implemented as crews managed the accident site and cleared the damaged vehicles from the roadway. Traffic in the area was heavily impacted through the afternoon hours.
We extend our thoughts to the individuals injured in this crash and hope for their swift and complete recovery.
Highway Accidents and Injury Risks on I-280 in San Francisco
High-speed collisions on interstates like I-280 often result in complex multi-vehicle incidents due to limited reaction time and dense traffic patterns. Saturday’s crash near the San Jose Avenue ramp is a strong example of the risks faced by drivers navigating freeway interchanges in and around San Francisco.
Southbound I-280 is a primary commuter artery connecting San Francisco to Daly City and the Peninsula, and it frequently sees high-speed traffic mixed with aggressive merging behavior near on-ramps. In this case, two vehicles collided in the far-right lane—an area often used by drivers entering or exiting the highway. These conditions create a heightened risk for sudden-impact crashes, especially when drivers fail to adjust their speed or spacing.
Multi-vehicle accidents with multiple injured parties demand immediate coordination between fire crews, medical teams, and traffic units. For victims, the consequences can include serious physical injuries, vehicle loss, emotional distress, and complicated insurance proceedings. Even in cases where the damage appears moderate, underlying injuries such as concussions or soft tissue trauma can emerge later.
It’s crucial for crash victims to seek medical evaluation right away and to document the incident thoroughly. Whether you’re a daily commuter or an occasional traveler on I-280, understanding your rights after a collision can help you recover fully and hold the appropriate parties accountable.
If you’ve been involved in a freeway crash in the Bay Area, don’t hesitate to explore your options for care and compensation. Legal and medical guidance can make all the difference in the days and weeks following an accident.
When you’re injured on one of California’s busiest highways, quick action and reliable support are key. At Local Accident Reports, our mission is to connect victims with trusted professionals who can help them navigate recovery. From injury treatment to legal direction, we’re here to assist you every step of the way. Contact us today to find the support you deserve.
