San Mateo, CA (September 3, 2025) – A serious multi-vehicle crash late Tuesday night left at least one person with severe injuries on northbound U.S. Highway 101, just south of the Highway 92 interchange, according to the California Highway Patrol.
The collision occurred around 9:42 p.m. and involved at least four vehicles, including a Honda Civic and a Hyundai Elantra. One of the vehicles was reportedly overturned and left resting on its roof, indicating the forceful nature of the impact.
CHP units and medical personnel responded quickly to the scene to assist those involved. At least one individual suffered serious injuries as a result of the crash. The injured person was treated on-site before being transported to a nearby hospital for further care. Details on the number of other victims, if any, have not yet been released.
Lanes were temporarily closed on northbound US-101 as authorities worked to clear debris, assist victims, and conduct an initial investigation into the cause of the wreck.
Our thoughts go out to those hurt in this collision. We wish them strength and a full recovery.
Multi-Vehicle Collisions in California
Serious crashes involving multiple vehicles are a recurring concern on California’s major highways, particularly along fast-moving corridors like U.S. 101 near San Mateo. With a mix of commuter traffic and commercial vehicles, this stretch of road often sees dense conditions where even minor misjudgments can escalate into chain-reaction incidents.
In this case, the rollover of one vehicle and the report of severe injuries underscore the high-impact nature of the crash. Multi-car collisions often result in complex damage patterns and increase the risk of trauma, especially when vehicles overturn or spin out. Victims may suffer from broken bones, internal injuries, or long-term orthopedic complications.
While the precise cause of Tuesday night’s crash remains under investigation, contributing factors on highways frequently include speeding, sudden lane changes, following too closely, or impaired driving. Nighttime conditions further reduce visibility, making it harder for drivers to react to abrupt stops or obstacles ahead.
For victims, recovery may involve not just physical healing but navigating insurance claims, loss of income, and emotional distress. That’s why accessing timely support and information following a serious crash is critical.
If you or someone close to you was injured in a freeway collision, knowing your options and connecting with trusted support can help guide the next steps.
After a serious accident on California highways, having access to the right support is essential. At Local Accident Reports, we help connect injured victims with vital local resources to aid in recovery, legal navigation, and care. Reach out now to learn how we can help you move forward with confidence.