Sioux Falls, SD (July 22, 2025) – A multi-vehicle accident with reports of serious injuries occurred early Tuesday morning at the intersection of W 12th St and S Ebenezer Ave in western Sioux Falls. Emergency services responded to the scene shortly after 1:26 a.m., where multiple vehicles were involved in the collision.
Authorities confirmed that at least one person sustained serious injuries, with additional occupants possibly hurt. Medics and fire crews worked urgently to assess those involved, providing on-scene care and transporting injured victims to area hospitals for further treatment. The exact number of individuals injured has not been publicly released.
W 12th St was partially closed in the early morning hours as first responders secured the scene, managed damaged vehicles, and began their investigation into the crash. This section of roadway, which sees significant through-traffic even during late hours, was disrupted for several hours.
Sioux Falls Police are leading the investigation into what caused the crash. Potential contributing factors, such as impaired driving, fatigue, or failure to yield, are being reviewed.
We extend our sincere thoughts to those injured and affected by this serious overnight accident.
Overnight Multi-Vehicle Accidents in South Dakota
Crashes that occur during early morning hours, like the one at W 12th St and S Ebenezer Ave, often involve more serious injuries due to reduced visibility, lower alertness, and higher travel speeds on open roads. In South Dakota, nighttime and early morning collisions account for a disproportionate share of fatal and serious injury crashes—particularly in urban centers like Sioux Falls where major roads remain active around the clock.
Intersections such as W 12th St and S Ebenezer are common sites for collisions due to left turns, merging lanes, and unpredictable nighttime driver behavior. Multi-vehicle crashes in these areas can result in complicated injury patterns, including neck and back trauma, internal injuries, and long-term mobility concerns.
Injury victims may face significant challenges after such collisions, from physical recovery and emotional trauma to insurance disputes and time away from work. Accessing local resources and legal guidance early in the process can play a key role in improving outcomes and easing the burden.
If you or a loved one was hurt in this Sioux Falls crash, don’t wait to seek medical care and the information needed to protect your health and future.
After a serious crash like this one in Sioux Falls, getting the right help is essential. At Local Accident Reports, we assist injury victims in connecting with trusted local services, care providers, and recovery resources. Reach out today to begin navigating your next steps with confidence and support.