CENTERTOWN, Cole County, Mo., Nov. 12, 2026 — Three people suffered serious injuries in a two-vehicle crash on Tuesday afternoon, November 10, on westbound U.S. Highway 50 near Centertown. The crash happened at the intersection with Lookout Trail, according to the Missouri State Highway Patrol.
The patrol said a pickup truck driven by a 68-year-old Mokane man crossed the westbound lanes of Highway 50 and was struck on the driver's side by a car driven by a 24-year-old California, Missouri woman. The pickup then hit a road sign before coming to rest.
Both drivers and the car's passenger, a 48-year-old California, Missouri woman, were seriously hurt in the crash. The two women were taken to University Hospital in Columbia, while the Mokane man was taken to Capital Region Medical Center in Jefferson City.
The Missouri State Highway Patrol is continuing to look into the circumstances of the crash. Our thoughts are with those who were injured, and we wish them a full recovery.
More on Crashes in Centertown, MO
This crash happened on U.S. Highway 50 in Centertown, MO. We cover crashes across Cole County as they're reported, and you can browse the latest in our Cole County accident reports.
Frequently Asked Questions
Where do most traffic accidents happen?
Crashes are common at intersections and points where roads merge, where turning or crossing traffic creates the chance for a vehicle to enter another's path, as happened in this crash.
What injuries are most common in car accidents like this one?
T-bone or side-impact crashes frequently cause head, chest and abdominal injuries, along with broken bones, because there is less structure to absorb the impact compared to a frontal collision.