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Fatal Six-Vehicle Pileup on NB I-5 Off-Ramp to Genesee Ave in San Diego, CA

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November 10, 2026
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UNIVERSITY CITY, San Diego County, Calif., Nov. 10, 2026 — One person died and several others were hurt on Monday morning, November 9, after six vehicles collided on an interstate off-ramp in the University City area, according to the California Highway Patrol.

The crash was reported shortly before 8 a.m. on the ramp from northbound I-5 to Genesee Avenue. A San Diego police officer who arrived at the scene performed CPR on a person with severe injuries. That person was taken to a hospital and died there.

The ramp was shut down for more than an hour and reopened to traffic around 9:45 a.m., according to the CHP.

Multiple people were taken to hospitals for treatment after the crash.

The CHP's investigation into the crash remains open. Our sympathies are with the family of the person who lost their life, and we wish those injured a full recovery.

More on Crashes in University City, CA

This crash happened on I-5 in University City, CA. We cover crashes across San Diego County as they're reported, and you can browse the latest in our San Diego County accident reports.

Frequently Asked Questions

What factors make a crash more likely to be fatal?

Outcomes tend to depend on how many vehicles are involved, the speed at impact, and whether occupants were wearing seat belts. Multi-vehicle pileups on ramps or highways usually add risk because following vehicles may not have time to stop.

How does speed affect whether someone survives a crash?

Higher speeds mean more force transferred in a collision, which raises the chance of serious injury or death. Even modest reductions in speed can change the outcome of a crash.

Why does seat belt use matter so much?

Seat belts keep occupants from being thrown inside or out of the vehicle during a collision, which lowers the risk of severe injury in a crash like this one.

What should families do after a fatal crash?

Families can contact the investigating agency, in this case the CHP, for updates on the investigation and for information on obtaining an official crash report once one is completed.

1Seek treatment promptly after being injured in an accident. Your first priority should always be your health. Many providers offer treatment on a lien basis, meaning you can get the care you need now and pay later when your claim is resolved.
2Before speaking with an insurance company, make sure you have the facts. An official police report is the most reliable record of what happened and can help establish liability An experienced attorney can assist you in obtaining this report and using it to protect your interests.
3Consider having your case reviewed by a qualified attorney who can guide you through the next steps. They will safeguard your rights and pursue the compensation you deserve.

Focus on your recovery and
let trusted professionals handle the rest

Local Accident Reports compiles incident information from official agencies and credible local sources. Early reports can change as investigations continue, and we update our coverage as new details are confirmed. If you have direct knowledge that something here is inaccurate, contact us at (888) 657-1460 and we will review and correct the record.

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Available San Diego, California Featured Medical Provider
Accident & Wellness Group
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Pain Management Urgent Care
We treat our clients like family.
Available San Diego, California Personal Injury Lawyer
Rexford Law, PC
Rexford Law, PC
Experience
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Free Case Review Personal Injury Litigation
Your pain-free life, just around the corner
Available San Diego, California Featured Medical Provider
Accident & Wellness Group
Experience
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Pain Management Urgent Care

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