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Early Morning Fatal Crash Closes I-110 in Los Angeles, CA

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September 7, 2026
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Los Angeles, CA (September 7, 2026) – A fatal multi-vehicle collision was reported on southbound Interstate 110 just north of Slauson Avenue at about 1:30 a.m. on Saturday, September 5.

Initial reports described three to six vehicles involved. One vehicle was overturned on its roof, another was facing the wrong direction, and a third had come to rest against the center divider wall.

All southbound lanes were initially held as emergency units worked on the freeway. A hard closure later affected lanes two through four, and four tow trucks were ultimately requested.

A SigAlert was issued for an estimated two hours. The circumstances surrounding the accident remain under investigation.

We extend our sincere condolences to the family and loved ones of the person who lost their life.

Overturned Vehicles Can Extend Multi-Lane Freeway Closures

A vehicle resting on its roof can require extra working space before it can be safely moved. Crews may need to stabilize it, check the passenger compartment, and clear debris before towing equipment can approach.

Multi-vehicle wrecks can also leave cars scattered across several travel lanes or against barriers. Those final positions may prevent traffic from passing safely, even when some vehicles remain drivable.

Overnight freeway closures can create additional challenges because approaching motorists have less visibility and may encounter stopped traffic unexpectedly. Tow operations, debris removal, roadway inspections, and medical activity can all delay reopening. When several vehicles require removal, each step may need to be completed in sequence before normal traffic flow can resume.

1Seek treatment promptly after being injured in an accident. Your first priority should always be your health. Many providers offer treatment on a lien basis, meaning you can get the care you need now and pay later when your claim is resolved.
2Before speaking with an insurance company, make sure you have the facts. An official police report is the most reliable record of what happened and can help establish liability An experienced attorney can assist you in obtaining this report and using it to protect your interests.
3Consider having your case reviewed by a qualified attorney who can guide you through the next steps. They will safeguard your rights and pursue the compensation you deserve.

Focus on your recovery and
let trusted professionals handle the rest

Local Accident Reports compiles incident information from official agencies and credible local sources. Early reports can change as investigations continue, and we update our coverage as new details are confirmed. If you have direct knowledge that something here is inaccurate, contact us at (888) 657-1460 and we will review and correct the record.

Your Rights. Our Mission.
Available Los Angeles, California Personal Injury Lawyer
Nick V. Gharibian, Esq.
Gharibian Legal Group, LLP
Experience
7+ years
Free Case Review Personal Injury Litigation Police Report Request
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Injured?
We're here to help
Immediate Care Available. Don't wait
Your Rights. Our Mission.
Available Los Angeles, California Personal Injury Lawyer
Nick V. Gharibian, Esq.
Gharibian Legal Group, LLP
Experience
7+ years
Free Case Review Personal Injury Litigation Police Report Request
Doctor placeholder
Injured?
We're here to help
Immediate Care Available. Don't wait

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